Summary: Background: Sensitivity has been a key Food issue for Enhancer of zeste homolog 2 (EZH2) inhibitors in cancer therapy.The EZH2 inhibitor EPZ-6438 was first approved by the US Food and Drug Administration (FDA) in 2020.However, its inadequate anti-cancer activity in solid tumors limits its clinical application.In this study, we utilized the
Thirty years of optometric education at Turfloop (1975-2005): A historical and educational overview
It is always necessary to document his-torical events for the purpose of future gen-erations.The Department of Optometry at Turfloop had a complex development which needs to be documented; hence, the purpose of this article is to present a historical and educational overview of the optometric educa-tion at Turfloop, thirty years after its inception
Pulmonary hypertension in wild type mice and animals with genetic deficit in KCa2.3 and KCa3.1 channels.
In vascular biology, endothelial KCa2.3 and KCa3.1 channels contribute to arterial blood pressure regulation by producing membrane hyperpolarization and smooth muscle relaxation.The role of KCa2.3 and KCa3.1 channels in the pulmonary circulation is not fully established.Using mice with genetically encoded deficit of KCa2.3 and KCa3.1 channels, this
Noncontact Detection of Respiration Rate Based on Forward Scatter Radar
Bioradar-based noncontact breathing detection technology has been widely studied due to its superior detection performance.In this paper, a breath detection mechanism based on the change in radar cross section (RCS) is proposed by using a forward scatter radar and the deduction of the Masks mathematical model of the received signal.Furthermore, we